Immunological Sciences

TMS1 Rabbit Monoclonal Antibody

No images available

Catalog Number:MABN86764
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human TMS1
Reactivity:Human
Applications:WB 1:1000-1:5000,IP 1:10-1:100
Molecular Weight:Calculated MW:22 kDa; Observed MW:22 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:ASC; TMS; TMS1; CARD5; TMS-1

Applications

WB 1:1000-1:5000,IP 1:10-1:100

Immunogen

A synthetic peptide of human TMS1

Target Background

This gene encodes an adaptor protein that is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain (PYD) and a C-terminal caspase-recruitment domain (CARD). The PYD and CARD domains are members of the six-helix bundle death domain-fold superfamily that mediates assembly of large signaling complexes in the inflammatory and apoptotic signaling pathways via the activation of caspase. In normal cells, this protein is localized to the cytoplasm; however, in cells undergoing apoptosis, it forms ball-like aggregates near the nuclear periphery. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Synonyms:ASC; TMS; TMS1; CARD5; TMS-1

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

No documents available.