Immunological Sciences

TPP1 Rabbit Monoclonal Antibody

No images available

Catalog Number:MABN87440
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:Recombinant protein of human TPP1
Reactivity:Human,Mouse,Rat
Applications:WB 1:1000-1:5000,IHC 1:50-1:100
Molecular Weight:Calculated MW:61,35 kDa; Observed MW:61,48 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:CLN2; GIG1; LPIC; SCAR7; TPP-1

Applications

WB 1:1000-1:5000,IHC 1:50-1:100

Immunogen

Recombinant protein of human TPP1

Target Background

This gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification. Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the lysosome. [provided by RefSeq, Jul 2008]

Synonyms:CLN2; GIG1; LPIC; SCAR7; TPP-1

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

No documents available.