Immunological Sciences

Transcription Factor E3 Rabbit Monoclonal antibody

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Catalog Number:MABN02684
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:Recombinant protein of human TFE3
Reactivity:Human,Mouse
Applications:WB 1:500-1:1000,IHC 1:50-1:100,ICC/IF 1:50-1:200
Molecular Weight:Calculated MW: 62 kDa; Observed MW: 62 kDa
Purification:Affinity Purified
Form:Liquid
Synonyms:TFE3; BHLHE33; Transcription factor E3; Class E basic helix-loop-helix protein 33; bHLHe33

Applications

WB 1:500-1:1000,IHC 1:50-1:100,ICC/IF 1:50-1:200

Immunogen

Recombinant protein of human TFE3

Target Background

Transcription factor that specifically recognizes and binds E-box sequences (3'-CANNTG-5'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFEB or MITF. In association with TFEB, activates the expression of CD40L in T-cells, thereby playing a role in T-cell-dependent antibody responses in activated CD4(+) T-cells and thymus-dependent humoral immunity.

Synonyms:TFE3; BHLHE33; Transcription factor E3; Class E basic helix-loop-helix protein 33; bHLHe33

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

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