TRIB3 Rabbit Polyclonal Antibody

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Catalog Number:ABN00326
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Polyclonal
Immunogen:A synthetic peptide of human TRIB3
Reactivity:Human
Applications:WB 1:500-1:1000,IP 1:20-1:50
Molecular Weight:Calculated MW: 40 kDa; Observed MW: 40 kDa
Purification:Affinity Chromatography
Form:Liquid
Synonyms:C20orf97; NIPK; SINK; SKIP3; TRB3; Trib3; Tribbles homolog 3; Tribbles pseudokinase 3; Tribbles3

Applications

WB 1:500-1:1000,IP 1:20-1:50

Immunogen

A synthetic peptide of human TRIB3

Target Background

Disrupts insulin signaling by binding directly to Akt kinases and blocking their activation. May bind directly to and mask the 'Thr-308' phosphorylation site in AKT1. Binds to ATF4 and inhibits its transcriptional activation activity. Interacts with the NF-kappa-B transactivator p65 RELA and inhibits its phosphorylation and thus its transcriptional activation activity.

Synonyms:C20orf97; NIPK; SINK; SKIP3; TRB3; Trib3; Tribbles homolog 3; Tribbles pseudokinase 3; Tribbles3

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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