Immunological Sciences

TRIM21 Mouse Monoclonal Antibody

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Catalog Number:MABN85011
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Mouse
Isotype:Mouse IgG1
Clone:Monoclonal
Immunogen:Purified recombinant human TRIM21 protein fragments expressed in E.coli.
Reactivity:Human
Applications:WB 1:500-1:1000
Molecular Weight:Calculated MW: 54 kDa; Observed MW: 50 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:SSA; RO52; SSA1; RNF81; Ro/SSA

Applications

WB 1:500-1:1000

Immunogen

Purified recombinant human TRIM21 protein fragments expressed in E.coli.

Target Background

This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The encoded protein is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus. Alternatively spliced transcript variants for this gene have been described but the full-length nature of only one has been determined.

Synonyms:SSA; RO52; SSA1; RNF81; Ro/SSA

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide,0.5%BSA and 50% glycerol.

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