TrkB Rabbit Monoclonal Antibody

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Catalog Number:MABN86702
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human TrkB
Reactivity:Human
Applications:WB 1:1000-1:5000,IHC 1:100-1:200,IP 1:10-1:100
Molecular Weight:Calculated MW:92 kDa; Observed MW:140,90 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:OBHD; TRKB; trk-B; GP145-TrkB

Applications

WB 1:1000-1:5000,IHC 1:100-1:200,IP 1:10-1:100

Immunogen

A synthetic peptide of human TrkB

Target Background

This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]

Synonyms:OBHD; TRKB; trk-B; GP145-TrkB

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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