TrpRS (12Y1) Rabbit Monoclonal Antibody

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Catalog Number:MABN19325
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human Tryptophanyl tRNA synthetase/WRS
Reactivity:Human,Mouse,Rat
Applications:WB 1:500-1:2000,IHC 1:100-1:500,FC 1:20-1:50,IF-P 1:100-1:500
Molecular Weight:53kDa
Purification:Affinity purification
Form:Liquid
Synonyms:WARS; GAMMA-2; HWRS; IFI53; IFP53; TrpRS; WRS;

Applications

WB 1:500-1:2000,IHC 1:100-1:500,FC 1:20-1:50,IF-P 1:100-1:500

Immunogen

A synthetic peptide of human Tryptophanyl tRNA synthetase/WRS

Target Background

Isoform 1, isoform 2 and T1-TrpRS have aminoacylation activity while T2-TrpRS lacks it. Isoform 2, T1-TrpRS and T2-TrpRS possess angiostatic activity whereas isoform 1 lacks it. T2-TrpRS inhibits fluid shear stress-activated responses of endothelial cells. Isoform 1, isoform 2 and T1-TrpRS have aminoacylation activity while T2-TrpRS lacks it. Isoform 2, T1-TrpRS and T2-TrpRS possess angiostatic activity whereas isoform 1 lacks it. T2-TrpRS inhibits fluid shear stress-activated responses of endothelial cells. Regulates ERK, Akt, and eNOS activation pathways that are associated with angiogenesis, cytoskeletal reorganization and shear stress- responsive gene expression.

Synonyms:WARS; GAMMA-2; HWRS; IFI53; IFP53; TrpRS; WRS;

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

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