TRUB2 Rabbit Monoclonal Antibody

No images available

Catalog Number:MABN02723
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:Recombinant protein of human TRUB2
Reactivity:Human
Applications:WB 1:500-1:1000
Molecular Weight:Calculated MW: 37 kDa; Observed MW: 37 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:Mitochondrial mRNA pseudouridine synthase TRUB2

Applications

WB 1:500-1:1000

Immunogen

Recombinant protein of human TRUB2

Target Background

Minor enzyme contributing to the isomerization of uridine to pseudouridine (pseudouridylation) of specific mitochondrial mRNAs (mt-mRNAs) such as COXI and COXIII mt-mRNAs (PubMed:27974379). As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation (PubMed:27667664).

Synonyms:Mitochondrial mRNA pseudouridine synthase TRUB2

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

No documents available.