Immunological Sciences

Tyro3 Mouse Monoclonal Antibody

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Catalog Number:MABN80649
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Mouse
Isotype:Mouse IgG1
Clone:Monoclonal
Immunogen:Purified recombinant fragment of Tyro3 (aa138-321) expressed in E. Coli.
Reactivity:Human
Applications:ICC 1:200-1:1000,ELISA 1:5000-1:20000
Purification:Affinity Purification
Form:Liquid
Synonyms:BYK; Brt; Dtk; RSE; Sky; Tif; FLJ16467

Applications

ICC 1:200-1:1000,ELISA 1:5000-1:20000

Immunogen

Purified recombinant fragment of Tyro3 (aa138-321) expressed in E. Coli.

Target Background

Tyro3 (also known as Sky and Rse), with 890-amino acid protein (about 98kDa), belongs to the Axl/Tyro3 family of receptor tyrosine kinases, which also includes Axl and Mer.Gas6 (growth arrest-specific gene-6) is a ligand for all members of the Axl family and they play essential roles in spermatogenesis, immunoregulation, and phagocytosis.Tyro3 was expressed at high levels during postnatal development and in the adult in the cortex.Tyro3 and Gas6 have neurotrophic roles in the nervous system.In addition, the signalling interactions of Axl and Tyro3 may play roles in tumourigenesis, inflammation as well as other cell proliferative diseases.

Synonyms:BYK; Brt; Dtk; RSE; Sky; Tif; FLJ16467

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Ascitic fluid containing 0.03% sodium azide.

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