U1-C Rabbit Monoclonal Antibody

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Catalog Number:MABN87669
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human U1-C
Reactivity:Human,Mouse,Rat
Applications:WB 1:1000-1:5000,IHC 1:200-1:1000,ICC/IF 1:200-1:500,IP 1:20-1:50
Molecular Weight:Calculated MW:17 kDa; Observed MW:21 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:U1C; Yhc1

Applications

WB 1:1000-1:5000,IHC 1:200-1:1000,ICC/IF 1:200-1:500,IP 1:20-1:50

Immunogen

A synthetic peptide of human U1-C

Target Background

This gene encodes one of the specific protein components of the U1 small nuclear ribonucleoprotein (snRNP) particle required for the formation of the spliceosome. The encoded protein participates in the processing of nuclear precursor messenger RNA splicing. snRNP particles are attacked by autoantibodies frequently produced by patients with connective tissue diseases. The genome contains several pseudogenes of this functional gene. Alternative splicing results in a non-coding transcript variant.[provided by RefSeq, Oct 2009]

Synonyms:U1C; Yhc1

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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