U1A Rabbit Monoclonal Antibody

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Catalog Number:MABN84138
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthesized peptide derived from human U1A
Reactivity:Human,Mouse,Rat
Applications:WB 1:1000-1:2000,ICC 1:50-1:200,IP 1:20-1:50
Molecular Weight:31 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:Mud1; snRNP A; SNRPA; U1-A; U1A;;U1A

Applications

WB 1:1000-1:2000,ICC 1:50-1:200,IP 1:20-1:50

Immunogen

A synthesized peptide derived from human U1A

Target Background

Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1 snRNP is the first snRNP to interact with pre-mRNA. This interaction is required for the subsequent binding of U2 snRNP and the U4/U6/U5 tri-snRNP. SNRPA binds stem loop II of U1 snRNA. In a snRNP-free form (SF-A) may be involved in coupled pre-mRNA splicing and polyadenylation process.

Synonyms:Mud1; snRNP A; SNRPA; U1-A; U1A;;U1A

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

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