Immunological Sciences

UBE4B (1H16) Rabbit Monoclonal Antibody

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Catalog Number:MABN19537
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human UBE4B
Reactivity:Human,Mouse,Rat
Applications:WB 1:1000-1:5000
Molecular Weight:146kDa
Purification:Affinity purification
Form:Liquid
Synonyms:HDNB1; Ube4b; UBOX3; UFD2; UFD2a; Ufd2p;

Applications

WB 1:1000-1:5000

Immunogen

A synthetic peptide of human UBE4B

Target Background

Binds to the ubiquitin moieties of preformed conjugates and catalyzes ubiquitin chain assembly in conjunction with E1, E2, and E3. Ubiquitin-protein ligase that probably functions as an E3 ligase in conjunction with specific E1 and E2 ligases (By similarity). May also function as an E4 ligase mediating the assembly of polyubiquitin chains on substrates ubiquitinated by another E3 ubiquitin ligase (By similarity). May regulate myosin assembly in striated muscles together with STUB1 and VCP/p97 by targeting myosin chaperone UNC45B for proteasomal degradation (PubMed:17369820).

Synonyms:HDNB1; Ube4b; UBOX3; UFD2; UFD2a; Ufd2p;

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

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