Ubiquitin K63 Rabbit Monoclonal antibody
Western blot analysis of Ubiquitin (linkagespecific K63) in Hela, A549 lysates using Ubiquitin K63 antibody.
| Catalog Number: | MABN03251 |
| Conjugate: | Unconjugated |
| Size: | 100 ug |
| Concentration: | 0.13mg/ml |
| Host: | Rabbit |
| Isotype: | IgG |
| Immunogen: | A synthetic peptide of human Ubiquitin (linkage-specific K63) |
| Reactivity: | Human |
| Applications: | WB 1:500-1:1000,IHC 1:50-1:100,ICC/IF 1:50-1:200 |
| Molecular Weight: | Calculated MW: 26 kDa; Observed MW: 8 kDa for monomeric, a smear of bands for poly-ubiquitylated |
| Purification: | Affinity Purified |
| Form: | Liquid |
| Synonyms: | FLJ25987; MGC8385; ubiquitin B; Ubiquitin; UBCEP1; UBCEP2; RPS27A |
Plays an important role in the ubiquitin-proteasome pathway. Ubiquitin can be covalently linked to many cellular proteins by the ubiquitination process, which targets proteins for degradation by the 26S proteasome. Three components are involved in the target protein-ubiquitin conjugation process. Ubiquitin is first activated by forming a thiolester complex with the activation component E1; the activated ubiquitin is subsequently transferred to the ubiquitin-carrier protein E2, then from E2 to ubiquitin ligase E3 for final delivery to the epsilon-NH2 of the target protein lysine residue.
Applications
WB 1:500-1:1000,IHC 1:50-1:100,ICC/IF 1:50-1:200
Immunogen
A synthetic peptide of human Ubiquitin (linkage-specific K63)
