UCP1 Rabbit Monoclonal Antibody

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Catalog Number:MABN87643
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of mouse UCP1
Reactivity:Mouse,Rat
Applications:WB 1:500-1:2000,IHC 1:200-1:1000,IP 1:20-1:50
Molecular Weight:Calculated MW:33 kDa; Observed MW:33 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:Ucp; Slc25a7

Applications

WB 1:500-1:2000,IHC 1:200-1:1000,IP 1:20-1:50

Immunogen

A synthetic peptide of mouse UCP1

Target Background

Enables long-chain fatty acid binding activity; oxidative phosphorylation uncoupler activity; and purine ribonucleotide binding activity. Involved in several processes, including cellular response to cold; diet induced thermogenesis; and positive regulation of cold-induced thermogenesis. Acts upstream of or within brown fat cell differentiation and regulation of transcription by RNA polymerase II. Located in mitochondrial inner membrane. Is expressed in several structures, including adipose tissue; adrenal gland; submandibular gland; testis; and thymus. Human ortholog(s) of this gene implicated in hypertension and type 2 diabetes mellitus. Orthologous to human UCP1 (uncoupling protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Synonyms:Ucp; Slc25a7

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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