Immunological Sciences

ULBP1 (3U10) Rabbit Monoclonal Antibody

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Catalog Number:MABN19619
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:Recombinant protein of human ULBP1
Reactivity:Human
Applications:FC 1:50-1:100
Molecular Weight:28kDa
Purification:Affinity purification
Form:Liquid
Synonyms:Alcan beta; N2DL1; NKG2DL1; RAET1I; UL16; UL16 binding protein 1; ULBP1;

Applications

FC 1:50-1:100

Immunogen

Recombinant protein of human ULBP1

Target Background

Ligand for the NKG2D receptor, together with at least ULBP2 and ULBP3. ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transduction pathway. Binds and activates the KLRK1/NKG2D receptor, mediating natural killer cell cytotoxicity.

Synonyms:Alcan beta; N2DL1; NKG2DL1; RAET1I; UL16; UL16 binding protein 1; ULBP1;

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

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