Immunological Sciences

ULBP1 Rabbit Monoclonal Antibody

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Catalog Number:MABN86736
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human ULBP1
Reactivity:Human
Applications:WB 1:1000-1:5000,FC 1:100-1:500
Molecular Weight:Calculated MW:28 kDa; Observed MW:40 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:N2DL-1; RAET1I; NKG2DL1

Applications

WB 1:1000-1:5000,FC 1:100-1:500

Immunogen

A synthetic peptide of human ULBP1

Target Background

The protein encoded by this gene is a ligand of natural killer group 2, member D (NKG2D), an immune system-activating receptor on NK cells and T-cells. Binding of the encoded ligand to NKG2D leads to activation of several signal transduction pathways, including those of JAK2, STAT5, ERK and PI3K kinase/Akt. Also, in cytomegalovirus-infected cells, this ligand binds the UL16 glycoprotein and is prevented from activating the immune system. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015]

Synonyms:N2DL-1; RAET1I; NKG2DL1

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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