UPB1 Rabbit Monoclonal Antibody

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Catalog Number:MABN21230
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG,Kappa
Clone:Monoclonal
Immunogen:A synthetic peptide of human UPB1
Reactivity:Human
Applications:WB 1:1000-1:5000,IHC 1:100-1:300,IP 1:50-1:100
Molecular Weight:CalcuLated MW:;Observed MW:42kD
Purification:Protein A
Form:Liquid
Synonyms:UPB1;BUP1;Beta-ureidopropionase ;BUP-1;Beta-alanine synthase;N-carbamoyl-beta-alanine amidohydrolase;

Applications

WB 1:1000-1:5000,IHC 1:100-1:300,IP 1:50-1:100

Immunogen

A synthetic peptide of human UPB1

Target Background

Cell localization:Cytoplasm..This gene encodes a protein that belongs to the CN hydrolase family. Beta-ureidopropionase catalyzes the last step in the pyrimidine degradation pathway. The pyrimidine bases uracil and thymine are degraded via the consecutive action of dihydropyrimidine dehydrogenase (DHPDH), dihydropyrimidinase (DHP) and beta-ureidopropionase (UP) to beta-alanine and beta-aminoisobutyric acid, respectively. UP deficiencies are associated with N-carbamyl-beta-amino aciduria and may lead to abnormalities in neurological activity. [provided by RefSeq, Jul 2008]

Synonyms:UPB1;BUP1;Beta-ureidopropionase ;BUP-1;Beta-alanine synthase;N-carbamoyl-beta-alanine amidohydrolase;

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

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