USP13 Rabbit Polyclonal Antibody

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Catalog Number:ABN00260
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Polyclonal
Immunogen:A synthetic peptide of human USP13
Reactivity:Human,Mouse
Applications:WB 1:500-1:1000,ICC/IF 1:50-1:200,FC 1:50-1:100,IP 1:20-1:50
Molecular Weight:Calculated MW: 97 kDa; Observed MW: 97 kDa
Purification:Affinity Chromatography
Form:Liquid
Synonyms:Deubiquitinating enzyme 13; Isopeptidase T3; ISOT3; UBP13; USP13

Applications

WB 1:500-1:1000,ICC/IF 1:50-1:200,FC 1:50-1:100,IP 1:20-1:50

Immunogen

A synthetic peptide of human USP13

Target Background

Mediates deubiquitination of BECN1, a key regulator of autophagy, leading to stabilize the PIK3C3/VPS34-containing complexes. Also deubiquitinates USP10, an essential regulator of p53/TP53 stability.

Synonyms:Deubiquitinating enzyme 13; Isopeptidase T3; ISOT3; UBP13; USP13

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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