Immunological Sciences

USP24 Rabbit Polyclonal Antibody

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Catalog Number:ABN19670
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Polyclonal
Immunogen:The antiserum was produced against synthesized peptide derived from human USP24. AA range:21-70
Reactivity:Human,Mouse
Applications:IHC 1:100-1:300,ICC/IF 1:50-1:200,ELISA 1:5000-1:20000
Purification:Affinity purification
Form:Liquid
Synonyms:USP24; KIAA1057; Ubiquitin carboxyl-terminal hydrolase 24; Deubiquitinating enzyme 24; Ubiquitin thioesterase 24; Ubiquitin-specific-processing protease 24

Applications

IHC 1:100-1:300,ICC/IF 1:50-1:200,ELISA 1:5000-1:20000

Immunogen

The antiserum was produced against synthesized peptide derived from human USP24. AA range:21-70

Target Background

Modification of cellular proteins by ubiquitin is an essential regulatory mechanism controlled by the coordinated action of multiple ubiquitin-conjugating and deubiquitinating enzymes. USP24 belongs to a large family of cysteine proteases that function as deubiquitinating enzymes (Quesada et al., 2004 [PubMed 14715245]).[supplied by OMIM, Mar 2008],catalytic activity:Ubiquitin C-terminal thioester + H(2)O = ubiquitin + a thiol.,function:Involved in the ubiquitin-dependent proteolytic pathway in conjunction with the 26S proteasome.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the peptidase C19 family.,similarity:Contains 1 UBA domain.,

Synonyms:USP24; KIAA1057; Ubiquitin carboxyl-terminal hydrolase 24; Deubiquitinating enzyme 24; Ubiquitin thioesterase 24; Ubiquitin-specific-processing protease 24

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

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