USP28 Rabbit Monoclonal Antibody

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Catalog Number:MABN84008
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthesized peptide derived from human USP28
Reactivity:Human
Applications:WB 1:1000-1:2000,ICC 1:50-1:200,FC 1:20-1:100
Molecular Weight:Calculated MW: 122 kDa ; Observed MW: 135 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:KIAA1515; Ubiquitin carboxyl terminal hydrolase 28; Ubiquitin thioesterase 28; UBP28;;USP28

Applications

WB 1:1000-1:2000,ICC 1:50-1:200,FC 1:20-1:100

Immunogen

A synthesized peptide derived from human USP28

Target Background

Deubiquitinase involved in DNA damage response checkpoint and MYC proto-oncogene stability. Involved in DNA damage induced apoptosis by specifically deubiquitinating proteins of the DNA damage pathway such as CLSPN. Also involved in G2 DNA damage checkpoint, by deubiquitinating CLSPN, and preventing its degradation by the anaphase promoting complex/cyclosome (APC/C).

Synonyms:KIAA1515; Ubiquitin carboxyl terminal hydrolase 28; Ubiquitin thioesterase 28; UBP28;;USP28

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

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