VAMP2 Mouse Monoclonal Antibody
Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
| Catalog Number: | MABN82986 |
| Conjugate: | Unconjugated |
| Size: | 100ul |
| Concentration: | 1mg/ml |
| Host: | Mouse |
| Isotype: | Mouse IgG1 |
| Clone: | Monoclonal |
| Immunogen: | Purified recombinant fragment of human VAMP2 (AA: 2-89aa) expressed in E. Coli. |
| Reactivity: | Human, Mouse, Monkey, Rat |
| Applications: | IHC 1:200-1:1000,ELISA 1:5000-1:20000,FC 1:200-1:400 |
| Molecular Weight: | 7kDa |
| Purification: | Affinity purification |
| Form: | liquid |
| Synonyms: | SYB2; VAMP-2; NEDHAHM |
The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. This gene is thought to participate in neurotransmitter release at a step between docking and fusion. The protein forms a stable complex with syntaxin, synaptosomal-associated protein, 25 kD, and synaptotagmin. It also forms a distinct complex with synaptophysin. It is a likely candidate gene for familial infantile myasthenia (FIMG) because of its map location and because it encodes a synaptic vesicle protein of the type that has been implicated in the pathogenesis of FIMG.
Applications
IHC 1:200-1:1000,ELISA 1:5000-1:20000,FC 1:200-1:400
Immunogen
Purified recombinant fragment of human VAMP2 (AA: 2-89aa) expressed in E. Coli.
