VAMP2 Rabbit Monoclonal antibody

Immunocytochemistry analysis of VAMP2 (green) in Jurkat using VAMP2 antibody, and DAPI (blue).

Immunocytochemistry analysis of VAMP2 (green) in Jurkat using VAMP2 antibody, and DAPI (blue).

Catalog Number:MABN02751
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human VAMP2
Reactivity:Human,Mouse,Rat
Applications:WB 1:500-1:1000,ICC/IF 1:50-1:200,IP 1:20-1:50
Molecular Weight:13 kDa
Purification:Affinity purification
Form:liquid
Synonyms:vesicle-associated membrane protein 2 (synaptobrevin 2); SYB2; VAMP-2

The SNARE complex is involved in vesicular transport and membrane fusion, a process regulated by calcium. In neurons, VAMP2 is predominantly inserted in presynaptic vesicle membranes. Assembly of VAMP2 with the plasma membrane SNAREs syntaxin 1 and SNAP25 is a key event necessary for membrane fusion and neurotransmitter release.

Applications

WB 1:500-1:1000,ICC/IF 1:50-1:200,IP 1:20-1:50

Immunogen

A synthetic peptide of human VAMP2

Target Background

The SNARE complex is involved in vesicular transport and membrane fusion, a process regulated by calcium. In neurons, VAMP2 is predominantly inserted in presynaptic vesicle membranes. Assembly of VAMP2 with the plasma membrane SNAREs syntaxin 1 and SNAP25 is a key event necessary for membrane fusion and neurotransmitter release.

Synonyms:vesicle-associated membrane protein 2 (synaptobrevin 2); SYB2; VAMP-2

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein

Immunocytochemistry analysis of VAMP2 (green) in Jurkat using VAMP2 antibody, and DAPI (blue).

Western blot analysis of VAMP2 in mouse brain lysates using VAMP2 antibody.

Western blot analysis of VAMP2 in rat Brain lysates using VAMP2 antibody

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