VDAC1 Rabbit Polyclonal Antibody
Western blot analysis of Calreticulin in (1) HepG2 lysates; (2) Jurkat lysates using VDAC1 antibody.
| Catalog Number: | ABN03717 |
| Conjugate: | Unconjugated |
| Size: | 100μL |
| Concentration: | 1mg/ml |
| Host: | Rabbit |
| Isotype: | IgG |
| Clone: | Polyclonal |
| Immunogen: | A synthetic peptide of human VDAC1 |
| Reactivity: | Human,Mouse,Rat |
| Applications: | WB 1:500-1:1000,IHC 1:50-1:100 |
| Molecular Weight: | Calculated MW: 31 kDa; Observed MW: 31 kDa |
| Purification: | Affinity Chromatography |
| Form: | Liquid |
| Synonyms: | VDAC1; PORIN; PORIN-31-HL |
Voltage-dependent anion channel (VDAC), ubiquitously expressed and located in the outer mitochondrial membrane, is generally thought to be the primary means by which metabolites diffuse in and out of the mitochondria. In addition, this channel plays a role in apoptotic signaling. The change in mitochondrial permeability characteristic of apoptosis is mediated by Bcl-2 family proteins, which bind to VDAC, altering the channel kinetics.
Applications
WB 1:500-1:1000,IHC 1:50-1:100
Immunogen
A synthetic peptide of human VDAC1
