Immunological Sciences

VEGFA Rabbit Monoclonal Antibody

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Catalog Number:MABN21324
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG,Kappa
Clone:Monoclonal
Immunogen:A synthetic peptide of human VEGFA
Reactivity:Human,Mouse,Rat,
Applications:WB 1:2000-1:10000,IHC 1:1000-1:5000,ICC/IF 1:200-1:1000,ELISA 1:5000-1:20000,IP 1:50-1:200
Molecular Weight:CalcuLated MW:27kD;Observed MW:40kD
Purification:Protein A
Form:Liquid
Synonyms:VEGFA;VEGF;VascuLar endothelial growth factor A;VEGF-A;VascuLar permeability factor;VPF

Applications

WB 1:2000-1:10000,IHC 1:1000-1:5000,ICC/IF 1:200-1:1000,ELISA 1:5000-1:20000,IP 1:50-1:200

Immunogen

A synthetic peptide of human VEGFA

Target Background

Cell localization:Secreted.This gene is a member of the PDGF/VEGF growth factor family. It encodes a heparin-binding protein, which exists as a disulfide-linked homodimer. This growth factor induces proliferation and migration of vascular endothelial cells, and is essential for both physiological and pathological angiogenesis. Disruption of this gene in mice resulted in abnormal embryonic blood vessel formation. This gene is upregulated in many known tumors and its expression is correlated with tumor stage and progression. Elevated levels of this protein are found in patients with POEMS syndrome, also known as Crow-Fukase syndrome. Allelic variants of this gene have been associated with microvascular complications of diabetes 1 (MVCD1) and atherosclerosis. Alternatively spliced transcript variants encoding different isoforms have been described. There is also evidence for alternative translation initiation fro

Synonyms:VEGFA;VEGF;VascuLar endothelial growth factor A;VEGF-A;VascuLar permeability factor;VPF

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

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