VPS18 Rabbit Monoclonal Antibody

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Catalog Number:MABN84209
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthesized peptide derived from human VPS18
Reactivity:Human,Mouse,Rat
Applications:WB 1:1000-1:2000,ICC 1:50-1:200,FC 1:20-1:100
Molecular Weight:Calculated MW: 110 kDa ; Observed MW: 100 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:hVPS18; PEP3; vps18;;VPS18

Applications

WB 1:1000-1:2000,ICC 1:50-1:200,FC 1:20-1:100

Immunogen

A synthesized peptide derived from human VPS18

Target Background

Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes which are proposed to be involved in the Rab5-to-Rab7 endosome conversion probably implicating MON1A/B, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion.

Synonyms:hVPS18; PEP3; vps18;;VPS18

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

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