WAPL Rabbit Monoclonal Antibody

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Catalog Number:MABN84573
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthesized peptide derived from human WAPL
Reactivity:Human
Applications:WB 1:1000-1:2000,ICC 1:50-1:200,IP 1:20-1:50
Molecular Weight:Calculated MW: 133 kDa ; Observed MW: 160 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:FOE; WAPAL; WAPL; Wings apart like homolog;;WAPL

Applications

WB 1:1000-1:2000,ICC 1:50-1:200,IP 1:20-1:50

Immunogen

A synthesized peptide derived from human WAPL

Target Background

Regulator of sister chromatid cohesion in mitosis which negatively regulates cohesin association with chromatin.Involved in both sister chromatid cohesion during interphase and sister-chromatid resolution during early stages of mitosis. Couples DNA replication to sister chromatid cohesion. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair.

Synonyms:FOE; WAPAL; WAPL; Wings apart like homolog;;WAPL

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

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