WAVE 1 Rabbit Monoclonal Antibody

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Catalog Number:MABN02770
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:Recombinant protein of human WAVE 1
Reactivity:Human,Mouse,Rat
Applications:WB 1:500-1:1000
Molecular Weight:Calculated MW: 62 kDa; Observed MW: 90 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:WAVE; SCAR1; WAVE1

Applications

WB 1:500-1:1000

Immunogen

Recombinant protein of human WAVE 1

Target Background

Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex . As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes .

Synonyms:WAVE; SCAR1; WAVE1

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

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