WDR5 Rabbit Polyclonal Antibody

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Catalog Number:ABN00274
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Polyclonal
Immunogen:A synthetic peptide of human WDR5
Reactivity:Human,Mouse,Rat
Applications:WB 1:500-1:1000,IHC 1:50-1:100,FC 1:50-1:100
Molecular Weight:Calculated MW: 37 kDa; Observed MW: 37 kDa
Purification:Affinity Chromatography
Form:Liquid
Synonyms:WDR5; BIG3; WD repeat-containing protein 5; BMP2-induced 3-kb gene protein

Applications

WB 1:500-1:1000,IHC 1:50-1:100,FC 1:50-1:100

Immunogen

A synthetic peptide of human WDR5

Target Background

Contributes to histone modification. May position the N-terminus of histone H3 for efficient trimethylation at 'Lys-4'. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation.

Synonyms:WDR5; BIG3; WD repeat-containing protein 5; BMP2-induced 3-kb gene protein

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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