Immunological Sciences

XBP1 Rabbit Monoclonal antibody

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Catalog Number:MABN03817
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:Recombinant protein of human XBP1
Reactivity:Human,Mouse
Applications:WB 1:500-1:1000,IP 1:20-1:50
Molecular Weight:Calculated MW: 29 kDa; Observed MW: 29 kDa
Purification:Affinity Purified
Form:Liquid
Synonyms:XBP1; TREB5; XBP2; X-box-binding protein 1; XBP-1; Tax-responsive element-binding protein 5

Applications

WB 1:500-1:1000,IP 1:20-1:50

Immunogen

Recombinant protein of human XBP1

Target Background

Acts during endoplasmic reticulum stress (ER) by activating unfolded protein response (UPR) target genes via direct binding to the UPR element (UPRE). Binds DNA preferably to the CRE-like element 5'-GATGACGTG[TG]N(3)[AT]T-3', and also to some TPA response elements (TRE). Binds to the HLA DR-alpha promoter. Binds to the Tax-responsive element (TRE) of HTLV-I.

Synonyms:XBP1; TREB5; XBP2; X-box-binding protein 1; XBP-1; Tax-responsive element-binding protein 5

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

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