Immunological Sciences

XIAP Rabbit Monoclonal Antibody

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Catalog Number:MABN02777
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:Recombinant protein of human XIAP
Reactivity:Human,Mouse,Rat
Applications:WB 1:500-1:1000
Molecular Weight:Calculated MW: 56 kDa; Observed MW: 53 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:API3; ILP1; MIHA; XLP2; BIRC4; IAP-3; hIAP3; hIAP-3

Applications

WB 1:500-1:1000

Immunogen

Recombinant protein of human XIAP

Target Background

Multi-functional protein which regulates not only caspases and apoptosis, but also modulates inflammatory signaling and immunity, copper homeostasis, mitogenic kinase signaling, cell proliferation, as well as cell invasion and metastasis. Acts as a direct caspase inhibitor. Directly bind to the active site pocket of CASP3 and CASP7 and obstructs substrate entry. Inactivates CASP9 by keeping it in a monomeric, inactive state.

Synonyms:API3; ILP1; MIHA; XLP2; BIRC4; IAP-3; hIAP3; hIAP-3

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

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