YAP1 Rabbit Monoclonal Antibody

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Catalog Number:MABN02782
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide corresponding to target protein
Reactivity:Human
Applications:WB 1:500-1:1000,IHC 1:50-1:100,IP 1:20-1:50
Molecular Weight:Calculated MW: 54 kDa; Observed MW: 65 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:YAP1; YAP65; Yorkie homolog; 65 kDa Yes-associated protein; YAP65

Applications

WB 1:500-1:1000,IHC 1:50-1:100,IP 1:20-1:50

Immunogen

A synthetic peptide corresponding to target protein

Target Background

YAP (Yes-associated protein, YAP65) was identified based on its ability to associate with the SH3 domain of Yes. Transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis.

Synonyms:YAP1; YAP65; Yorkie homolog; 65 kDa Yes-associated protein; YAP65

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

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