Immunological Sciences

ZBTB16 Mouse Monoclonal Antibody

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Catalog Number:MABN80869
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Mouse
Isotype:Mouse IgG1
Clone:Monoclonal
Immunogen:Purified recombinant fragment of human ZBTB16 expressed in E. Coli.
Reactivity:Human
Applications:WB 1:500-1:2000,ICC 1:200-1:1000,ELISA 1:5000-1:20000
Molecular Weight:74kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:PLZF; ZNF145; ZBTB16

Applications

WB 1:500-1:2000,ICC 1:200-1:1000,ELISA 1:5000-1:20000

Immunogen

Purified recombinant fragment of human ZBTB16 expressed in E. Coli.

Target Background

This gene is a member of the Krueppel C2H2-type zinc-finger protein family and encodes a zinc finger transcription factor that contains nine Kruppel-type zinc finger domains at the carboxyl terminus. This protein is located in the nucleus, is involved in cell cycle progression, and interacts with a histone deacetylase. Specific instances of aberrant gene rearrangement at this locus have been associated with acute promyelocytic leukemia (APL). Alternate transcriptional splice variants have been characterized. Tissue specificity: Within the hematopoietic system, PLZF is expressed in bone marrow, early myeloid cell lines and peripheral blood mononuclear cells. Also expressed in the ovary, and at lower levels, in the kidney and lung.

Synonyms:PLZF; ZNF145; ZBTB16

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide.

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