Zic1 (4R9) Rabbit Monoclonal Antibody
Western blot analysis of Zic1 expression in SW480 cell lysate.
| Catalog Number: | MABN20103 |
| Conjugate: | Unconjugated |
| Size: | 100ul |
| Concentration: | 1mg/ml |
| Host: | Rabbit |
| Isotype: | IgG |
| Clone: | 4R9 |
| Immunogen: | A synthetic peptide of human Zic1 |
| Reactivity: | Human |
| Applications: | WB 1:1000-1:5000,ICC/IF 1:100-1:200,FC 1:50-1:100 |
| Molecular Weight: | 48kDa |
| Purification: | Affinity purification |
| Form: | liquid |
| Synonyms: | ZIC; Zic protein member 1; Zinc finger protein 201; Zinc finger protein ZIC1; ZNF201; |
Acts as a transcriptional activator. Involved in neurogenesis. Plays important roles in the early stage of organogenesis of the CNS, as well as during dorsal spinal cord development and maturation of the cerebellum. Involved in the spatial distribution of mossy fiber (MF) neurons within the pontine gray nucleus (PGN). Plays a role in the regulation of MF axon pathway choice. Promotes MF migration towards ipsilaterally-located cerebellar territories. Acts as a transcriptional activator. Involved in neurogenesis. Plays important roles in the early stage of organogenesis of the CNS, as well as during dorsal spinal cord development and maturation of the cerebellum. Involved in the spatial distribution of mossy fiber (MF) neurons within the pontine gray nucleus (PGN). Plays a role in the regulation of MF axon pathway choice. Promotes MF migration towards ipsilaterally-located cerebellar territories. May have a role in shear flow mechanotransduction in osteocytes. Retains nuclear GLI1 and GLI3 in the cytoplasm. Binds to the minimal GLI-consensus sequence 5'-TGGGTGGTC-3' (By similarity).
Applications
WB 1:1000-1:5000,ICC/IF 1:100-1:200,FC 1:50-1:100
Immunogen
A synthetic peptide of human Zic1